PHG
L-prolyl-L-hydroxyprolyl-glycine
Pro-Hyp-Gly Amino Acids · MW: 285.29
Amino Acids
Pro-Hyp-Gly
Molecular Weight
285.29
Half-life
transient; hours
Research Score
4.5
Studies
87
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is PHG?
A collagen-derived tripeptide found among hydrolysate peptides after enzymatic digestion of collagen. It is part of the low-molecular-weight peptide fraction associated with oral collagen products.
Key Benefits & Mechanisms
skin support
joint support
extracellular-matrix signaling
Research Summary
This tripeptide has been reported among collagen hydrolysate digestion products and in absorption studies of small collagen peptides. Evidence suggests collagen-derived tripeptides can appear in circulation and may act as signaling molecules, though individual clinical effects are not established.
Related Peptides
Pro-Gly-Pro
L-Prolyl-glycyl-L-proline
A collagen-breakdown tripeptide generated during matrix proteolysis, especially from collagen-rich tissues. It is best known as a neutrophil chemoattractant and a biomarker of collagen turnover.
Collagen PeptidesDGEA
Asp-Gly-Glu-Ala
A type I collagen-derived tetrapeptide used in cell-adhesion and bone-biology research. It interacts with collagen-related signaling pathways and is commonly studied in scaffolds and wound-healing models.
Collagen PeptidesGFOGER
Gly-Phe-Hyp-Gly-Glu-Arg
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Collagen PeptidesGPH
Glycyl-L-prolyl-L-hydroxyproline
A collagen-derived tripeptide commonly detected after oral collagen hydrolysate intake. It is studied as a circulating marker peptide and for possible extracellular-matrix signaling.
Collagen Peptides