MBP83-99
Myelin basic protein 83-99
17 Amino Acids · MW: ~2013 Da
Amino Acids
17
Molecular Weight
~2013 Da
Half-life
minutes to hours
Research Score
4.5
Studies
89
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is MBP83-99?
An immunodominant human myelin basic protein epitope used in antigen-specific tolerance studies for multiple sclerosis. It has been investigated as a peptide immunotherapy to reduce autoreactive T-cell responses without broad immunosuppression.
Key Benefits & Mechanisms
antigen-specific tolerance
Th1/Th17 dampening
relapse reduction
Research Summary
A classic myelin epitope in MS immunology and tolerance research. It is used to test whether peptide administration can bias immunity toward regulatory pathways.
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