MBP Ac1-9
Myelin basic protein Ac1-9 (Ac-ASQKRPSQR)
9 Amino Acids · MW: ~1099 Da
Amino Acids
9
Molecular Weight
~1099 Da
Half-life
minutes to hours
Research Score
4.4
Studies
90
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is MBP Ac1-9?
An acetylated N-terminal myelin basic protein epitope used to induce antigen-specific tolerance in multiple sclerosis models. It is explored for skewing responses toward regulatory T cells while reducing encephalitogenic T-cell activity.
Key Benefits & Mechanisms
antigen-specific tolerance
Treg expansion
reduced autoreactivity
Research Summary
Used in peptide-immunotherapy and tolerance-induction research for autoimmune demyelination. The goal is to dampen pathogenic T-cell responses without broad immunosuppression.
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