LyP1
LyP-1
CGNKRTRGC Amino Acids · MW: 991.1
Amino Acids
CGNKRTRGC
Molecular Weight
991.1
Half-life
~0.2-1 h
Research Score
4.2
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is LyP1?
A tumor-homing cyclic peptide that preferentially localizes to lymphatic and some hypoxic tumor compartments. It has been used to enhance delivery of drugs and nanoparticles to breast tumor and metastasis models.
Key Benefits & Mechanisms
tumor homing
lymphatic targeting
metastatic lesion delivery
Research Summary
LyP-1 is a documented tumor-homing peptide used in targeted nanocarriers and conjugates. Preclinical studies show improved accumulation in tumor-associated lymphatic and hypoxic regions compared with untargeted controls.
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Drug Delivery