Insulin Glargine
Insulin glargine (A21Gly,B31Arg,B32Arg human insulin analog)
51 Amino Acids · MW: 6063.6 Da
Amino Acids
51
Molecular Weight
6063.6 Da
Half-life
About 12-24 hours
Research Score
4.9
Studies
13000
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Insulin Glargine?
A long-acting basal insulin analog engineered for slow release from the subcutaneous depot. It provides relatively flat day-long insulin coverage and is used to control fasting glucose.
Key Benefits & Mechanisms
Once-daily basal coverage
Smooth action profile
Lower nocturnal hypoglycemia risk
Improves fasting glucose control
Research Summary
Clinical and translational studies support its use as a basal comparator because of prolonged absorption and stable glycemic control. It is heavily used in basal-bolus regimen research and insulin-delivery optimization studies.
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