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Insulin Degludec

Insulin degludec (desB30, acylated ultra-long-acting insulin analog)

50 Amino Acids · MW: 6103.9 Da

Amino Acids

50

Molecular Weight

6103.9 Da

Half-life

More than 25 hours

Research Score

4.8

Studies

7000

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is Insulin Degludec?

An ultra-long-acting insulin analog designed with a fatty-acid side chain to form a slow-release depot. It is valued for very flat pharmacokinetics and flexible once-daily basal dosing.

Key Benefits & Mechanisms

Ultra-long basal coverage

Lower day-to-day variability

Reduced nocturnal hypoglycemia

Flexible dosing time

Research Summary

Studies highlight prolonged action and lower glycemic variability compared with many other basal insulins. It is frequently used in research on ultra-long basal coverage and hypoglycemia reduction.