HGP
L-hydroxyprolyl-glycyl-L-proline
Hyp-Gly-Pro Amino Acids · MW: 285.29
Amino Acids
Hyp-Gly-Pro
Molecular Weight
285.29
Half-life
transient; hours
Research Score
4.3
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is HGP?
A collagen-derived tripeptide sequence isomer that can arise from collagen and gelatin hydrolysis. It is part of the set of small proline-hydroxyproline-rich peptides detected after collagen intake.
Key Benefits & Mechanisms
skin support
joint matrix support
collagen peptide marker
Research Summary
Hydroxyprolyl-glycyl-proline is a documented collagen-derived tripeptide sequence observed in collagen hydrolysate peptide pools. Like related tripeptides, it is best viewed as a bioavailable marker peptide with plausible matrix-signaling roles rather than a fully established drug-like agent.
Related Peptides
Pro-Gly-Pro
L-Prolyl-glycyl-L-proline
A collagen-breakdown tripeptide generated during matrix proteolysis, especially from collagen-rich tissues. It is best known as a neutrophil chemoattractant and a biomarker of collagen turnover.
Collagen PeptidesDGEA
Asp-Gly-Glu-Ala
A type I collagen-derived tetrapeptide used in cell-adhesion and bone-biology research. It interacts with collagen-related signaling pathways and is commonly studied in scaffolds and wound-healing models.
Collagen PeptidesGFOGER
Gly-Phe-Hyp-Gly-Glu-Arg
A high-affinity type I collagen integrin-binding motif containing hydroxyproline. It is heavily used in biomaterials to promote cell attachment, osteoblast behavior, and matrix organization.
Collagen PeptidesGPH
Glycyl-L-prolyl-L-hydroxyproline
A collagen-derived tripeptide commonly detected after oral collagen hydrolysate intake. It is studied as a circulating marker peptide and for possible extracellular-matrix signaling.
Collagen Peptides