HG
L-hydroxyprolyl-glycine
Hyp-Gly Amino Acids · MW: 188.18
Amino Acids
Hyp-Gly
Molecular Weight
188.18
Half-life
transient; hours
Research Score
4.4
Studies
86
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is HG?
A simple collagen-derived dipeptide containing hydroxyproline and glycine. It is a common digestion product of collagen and gelatin proteins.
Key Benefits & Mechanisms
collagen metabolism marker
connective tissue support
oral collagen bioavailability marker
Research Summary
Hydroxyprolyl-glycine has been identified among collagen digestion products and in bioavailability studies of collagen hydrolysates. It is considered part of the absorbable peptide pool that may contribute to downstream skin and joint effects seen with collagen peptide supplementation.
Related Peptides
Pro-Gly-Pro
L-Prolyl-glycyl-L-proline
A collagen-breakdown tripeptide generated during matrix proteolysis, especially from collagen-rich tissues. It is best known as a neutrophil chemoattractant and a biomarker of collagen turnover.
Collagen PeptidesDGEA
Asp-Gly-Glu-Ala
A type I collagen-derived tetrapeptide used in cell-adhesion and bone-biology research. It interacts with collagen-related signaling pathways and is commonly studied in scaffolds and wound-healing models.
Collagen PeptidesGFOGER
Gly-Phe-Hyp-Gly-Glu-Arg
A high-affinity type I collagen integrin-binding motif containing hydroxyproline. It is heavily used in biomaterials to promote cell attachment, osteoblast behavior, and matrix organization.
Collagen PeptidesGPH
Glycyl-L-prolyl-L-hydroxyproline
A collagen-derived tripeptide commonly detected after oral collagen hydrolysate intake. It is studied as a circulating marker peptide and for possible extracellular-matrix signaling.
Collagen Peptides