GAD65 555-567
Glutamic acid decarboxylase 65 555-567
13 Amino Acids · MW: ~1726 Da
Amino Acids
13
Molecular Weight
~1726 Da
Half-life
minutes to hours
Research Score
4.0
Studies
84
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is GAD65 555-567?
A diabetes-associated glutamic acid decarboxylase 65 epitope studied for antigen-specific tolerance in type 1 diabetes. It is used to evaluate whether peptide therapy can preserve beta-cell function while minimizing systemic immunosuppression.
Key Benefits & Mechanisms
beta-cell sparing
antigen-specific tolerance
autoantibody modulation
Research Summary
A real autoantigenic peptide explored in type 1 diabetes immune-tolerance research. The central idea is to induce regulatory immunity against a disease-relevant epitope rather than suppressing the whole immune system.
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