FGL
Phe-Gly-Leu (NCAM-derived FGL peptide)
3 Amino Acids · MW: 323.40 Da
Amino Acids
3
Molecular Weight
323.40 Da
Half-life
minutes
Research Score
3.8
Studies
66
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is FGL?
A short NCAM-mimetic peptide studied for neurite outgrowth, remyelination, and synaptic plasticity. It is especially relevant to MS-style demyelination and broader neurorepair concepts.
Key Benefits & Mechanisms
MS
remyelination
neurorepair
Research Summary
FGL is one of the more relevant short peptides for demyelination and repair-oriented CNS research. It is a research lead rather than an approved therapy.
Related Peptides
Glypromate
GPE
A tripeptide composed of glycine-proline-glutamic acid and an endogenous IGF-1–related fragment. It has been studied in hypoxia-ischemia, stroke, and TBI models for neuronal survival and repair signaling.
NeurologicalACTH (1-39)
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe
ACTH(1-39) is the full-length corticotropin peptide used clinically in MS relapse management via repository corticotropin products. Its relevance is primarily immunomodulatory and anti-inflammatory rather than disease-modifying.
Neurological