Cerebrolysin
Porcine Brain-Derived Peptide Mixture
Amino Acids
N/A
Molecular Weight
Mixture (< 10,000 Da)
Half-life
~minutes to hours
Research Score
4.6
Studies
245
Storage
N/A
What is Cerebrolysin?
Cerebrolysin is a mixture of low-molecular-weight neuropeptides and free amino acids derived from porcine brain tissue. It has neurotrophic properties similar to naturally occurring nerve growth factors. Approved in many countries for stroke recovery, traumatic brain injury, and dementia.
Key Benefits & Mechanisms
Neurotrophic factor-like activity
Neuroprotection in stroke and TBI
Improved cognitive function in dementia
Promotes neuronal survival and plasticity
Reduces amyloid pathology
Enhanced recovery from brain injuries
Synaptic repair and neurogenesis
Research Summary
Cerebrolysin has extensive clinical evidence with over 200 clinical studies. Approved in more than 45 countries for neurological conditions. Cochrane reviews show moderate evidence for vascular dementia. Large-scale trials (CARS, CASTA) demonstrate benefits in stroke recovery.
Related Peptides
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Selank is a synthetic peptide analog of the naturally occurring tetrapeptide tuftsin. Developed in Russia, it has anxiolytic and nootropic properties. It modulates the expression of brain-derived neurotrophic factor (BDNF) and serotonin.
NootropicSemax
Synthetic ACTH Analog (Met-Glu-His-Phe-Pro-Gly-Pro)
Semax is a synthetic heptapeptide analog of ACTH(4-7) developed at the Institute of Molecular Genetics in Russia. It enhances cognitive function, memory, and neuroprotection through BDNF upregulation and modulation of serotonergic and dopaminergic systems. Approved in Russia as a nootropic and neuroprotective agent.
NootropicDihexa
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Dihexa is a potent nootropic peptide derived from angiotensin IV. It is reported to be approximately 10 million times more potent than BDNF at promoting synaptic connectivity. It enhances cognitive function by driving new synapse formation through hepatocyte growth factor (HGF) pathway activation.
NootropicNA-Selank
N-Acetyl Selank (Amidate)
NA-Selank is the acetylated and amidated version of Selank, designed for enhanced stability and bioavailability. The N-acetyl modification protects against enzymatic degradation, resulting in longer-lasting effects. It maintains all the anxiolytic and cognitive benefits of Selank with improved pharmacokinetics.
Nootropic