Somatostatin-14 vs hGHRH(1-40)OH
Head-to-head comparison of Somatostatin-14 (Somatostatin (somatotropin release-inhibiting factor, 14-amino-acid form)) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Somatostatin-14 | hGHRH(1-40)OH |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Full Name | Somatostatin (somatotropin release-inhibiting factor, 14-amino-acid form) | Human growth hormone-releasing factor (1-40) hydroxyl |
| Molecular Weight | 1637.9 Da | N/A |
| Half-Life | 1-3 minutes | 5-20 minutes |
| Amino Acids | 14 | 40 |
| Typical Dose | Research-only; microgram-scale bolus or infusion | 1-2 mcg/kg |
| Route | Intravenous/Subcutaneous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 2000 | 85 |
| Research Status | Pre-clinical | Clinical Research |
Somatostatin-14 Benefits
- ✓GH suppression reference
- ✓somatostatin receptor mapping
- ✓GI hormone inhibition
- ✓endocrine research tool
hGHRH(1-40)OH Benefits
- ✓GH secretion research
- ✓fragment-activity comparison
- ✓receptor binding studies
- ✓axis physiology modeling
Somatostatin-14 Dosing
250 mcg IV bolus|250 mcg SC in short studies|continuous IV infusion in experimental settings
hGHRH(1-40)OH Dosing
1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies
Somatostatin-14 Side Effects
- ⚠bradycardia
- ⚠nausea
- ⚠glucose changes
hGHRH(1-40)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠lightheadedness
Research Overview
Somatostatin-14
Somatostatin-14 established the core inhibitory biology of the GH axis and is widely used to study receptor subtype signaling. It remains a benchmark ligand for comparing synthetic analogs and endocrine pharmacology.
hGHRH(1-40)OH
Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.