Somatostatin-14
Somatostatin (somatotropin release-inhibiting factor, 14-amino-acid form)
14 Amino Acids · MW: 1637.9 Da
Amino Acids
14
Molecular Weight
1637.9 Da
Half-life
1-3 minutes
Research Score
4.9
Studies
2000
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Somatostatin-14?
Native 14-amino-acid hypothalamic peptide that strongly inhibits pituitary growth hormone release. It also suppresses several gastrointestinal and pancreatic hormones, making it a foundational reference molecule for somatostatin receptor biology.
Key Benefits & Mechanisms
GH suppression reference
somatostatin receptor mapping
GI hormone inhibition
endocrine research tool
Research Summary
Somatostatin-14 established the core inhibitory biology of the GH axis and is widely used to study receptor subtype signaling. It remains a benchmark ligand for comparing synthetic analogs and endocrine pharmacology.
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