MK-677 vs Arenicin-1
Head-to-head comparison of MK-677 (Ibutamoren Mesylate (MK-677)) and Arenicin-1 (Arenicin-1) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | MK-677 | Arenicin-1 |
|---|---|---|
| Category | Growth Hormone | Marine-Derived |
| Full Name | Ibutamoren Mesylate (MK-677) | Arenicin-1 |
| Molecular Weight | 528.662 g/mol | 2079 Da |
| Half-Life | ~24 hours | n/a |
| Amino Acids | Non-peptide compound | 21 |
| Typical Dose | — | n/a |
| Route | — | preclinical |
| Purity | >99% | ≥98% |
| Studies Count | 120 | 76 |
| Research Status | Active Research | Pre-clinical |
MK-677 Benefits
- ✓Oral GH secretagogue, 24-hour GH elevation, increases IGF-1, improves sleep quality, increases lean mass, does not suppress natural GH
Arenicin-1 Benefits
- ✓antimicrobial
- ✓anti-biofilm
- ✓membrane-active
MK-677 Dosing
10-25 mg orally once daily before bedtime. 25 mg is the most studied dose. Can be used long-term without cycling.
Arenicin-1 Dosing
bacterial infection|biofilm disruption
MK-677 Side Effects
- ⚠Increased appetite, mild water retention, drowsiness, transient numbness, mild increase in fasting blood glucose with long-term use.
Arenicin-1 Side Effects
- ⚠Arenicola marina
Research Overview
MK-677
A landmark 2-year study in elderly adults demonstrated significant increases in lean mass, GH pulsatility, and IGF-1 to youthful ranges. Selectively agonizes GHS-R1a without increasing cortisol or prolactin.
Arenicin-1
Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.
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