Arenicin-1 vs L-692,429

Head-to-head comparison of Arenicin-1 (Arenicin-1) and L-692,429 (L-692,429) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyArenicin-1L-692,429
CategoryMarine-DerivedGrowth Hormone
Full NameArenicin-1L-692,429
Molecular Weight2079 DaN/A
Half-Lifen/aunknown / study-dependent
Amino Acids21N/A
Typical Dosen/a0.03-0.1 mg/kg
RoutepreclinicalOral
Purity≥98%≥98%
Studies Count7630
Research StatusPre-clinicalPre-clinical

Arenicin-1 Benefits

  • antimicrobial
  • anti-biofilm
  • membrane-active

L-692,429 Benefits

  • potent GHSR agonism
  • oral bioactivity in models
  • validates ghrelin pathway
  • useful research probe

Arenicin-1 Dosing

bacterial infection|biofilm disruption

L-692,429 Dosing

0.03-0.1 mg/kg in early studies|single oral or short-course research dosing|serial GH sampling recommended

Arenicin-1 Side Effects

  • Arenicola marina

L-692,429 Side Effects

  • increased appetite
  • glucose intolerance
  • transient prolactin changes

Research Overview

Arenicin-1

Marine annelid peptide with strong preclinical antibacterial activity and a stable structural motif that is useful for peptide engineering.

L-692,429

L-692,429 was important in early GH secretagogue research because it showed that nonpeptide molecules could trigger robust GH release. It remains a classic tool compound for studying receptor-mediated GH pulsatility and appetite signaling.

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Common Stacking Partners

Arenicin-1 stacks with:

Arenicola marinabeta-hairpinantibiotic

L-692,429 stacks with:

Receptor assaysEndocrine studies
marine-derivedbioactiveantimicrobial peptidebiofilmtool-compoundgh-secretagogueghrelin-pathway