Cholecystokinin-8 vs hGHRH(1-40)OH
Head-to-head comparison of Cholecystokinin-8 (Cholecystokinin (sulfated C-terminal octapeptide, CCK-8)) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Cholecystokinin-8 | hGHRH(1-40)OH |
|---|---|---|
| Category | Endocrine Peptides | Growth Hormone |
| Full Name | Cholecystokinin (sulfated C-terminal octapeptide, CCK-8) | Human growth hormone-releasing factor (1-40) hydroxyl |
| Molecular Weight | 1143.2 Da | N/A |
| Half-Life | 1-2 min | 5-20 minutes |
| Amino Acids | DY(SO3H)MGWMDF-NH2 | 40 |
| Typical Dose | physiologic low-picomolar-nanomolar range|research-dependent | 1-2 mcg/kg |
| Route | endogenous secretion|research IV/SC | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 97 | 85 |
| Research Status | Endogenous | Clinical Research |
Cholecystokinin-8 Benefits
- ✓gallbladder contraction
- ✓pancreatic enzyme release
- ✓satiety signaling
hGHRH(1-40)OH Benefits
- ✓GH secretion research
- ✓fragment-activity comparison
- ✓receptor binding studies
- ✓axis physiology modeling
Cholecystokinin-8 Dosing
physiologic secretion|research-dependent
hGHRH(1-40)OH Dosing
1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies
Cholecystokinin-8 Side Effects
- ⚠abdominal cramping
- ⚠nausea
- ⚠biliary contraction
hGHRH(1-40)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠lightheadedness
Research Overview
Cholecystokinin-8
CCK-8 is a canonical gut hormone fragment with extensive documentation in digestive physiology and appetite control. Sulfation of the tyrosine residue is important for high-affinity receptor activity.
hGHRH(1-40)OH
Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.
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