Tumstatin
Collagen IV Alpha-3 NC1 Domain (Tumstatin)
N/A Amino Acids · MW: ~28,000 Da
Amino Acids
N/A
Molecular Weight
~28,000 Da
Half-life
N/A
Research Score
4.0
Studies
75
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Tumstatin?
Tumstatin is a collagen IV-derived fragment that inhibits angiogenesis and can induce apoptosis in endothelial cells. It is studied as a selective suppressor of pathologic vessel growth in tumor biology.
Key Benefits & Mechanisms
angiogenesis inhibition
endothelial apoptosis
tumor vessel suppression
mechanistic research tool
Research Summary
Tumstatin has demonstrated potent anti-vascular effects in preclinical cancer models through integrin-linked and translational control pathways. It remains primarily a translational and mechanistic research molecule rather than a routine clinical drug.
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