Somatrogon
Recombinant human growth hormone fused to three copies of the C-terminal peptide of hCG beta
275 Amino Acids · MW: 47000 Da
Amino Acids
275
Molecular Weight
47000 Da
Half-life
28-45 hours
Research Score
4.3
Studies
25
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Somatrogon?
Somatrogon is a long-acting GH fusion protein engineered for once-weekly administration. The C-terminal peptide extensions prolong circulation time while preserving growth hormone activity.
Key Benefits & Mechanisms
once-weekly dosing
growth velocity support
sustained gh signaling
improved adherence
Research Summary
Somatrogon has been evaluated in pediatric GH deficiency studies as a once-weekly replacement option. Data show maintained IGF-1 exposure and growth outcomes comparable to daily GH in study populations.
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