PMX53
Cyclic Complement C5a Receptor Antagonist Peptide PMX53
6 Amino Acids · MW: ≈790 Da
Amino Acids
6
Molecular Weight
≈790 Da
Half-life
Several hours
Research Score
4.2
Studies
70
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is PMX53?
A cyclic hexapeptide designed to block complement C5a receptor signaling. It has been studied in inflammatory and autoimmune settings where complement-driven leukocyte recruitment contributes to tissue damage.
Key Benefits & Mechanisms
complement pathway inhibition
neutrophil recruitment reduction
autoimmune/inflammatory research
tissue-injury modulation
Research Summary
PMX53 is a well-characterized tool compound for blocking complement-driven immune recruitment and tissue damage. It has been used in research on psoriasis, arthritis, and other complement-mediated inflammatory diseases.
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