Pleurocidin
Pleurocidin (winter flounder antimicrobial peptide)
25 Amino Acids · MW: ~2.8 kDa
Amino Acids
25
Molecular Weight
~2.8 kDa
Half-life
NR
Research Score
4.5
Studies
82
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Pleurocidin?
Pleurocidin is a 25-residue antimicrobial peptide first isolated from winter flounder. It is studied for antimicrobial, anticancer, and anti-endotoxin activity.
Key Benefits & Mechanisms
antimicrobial
anticancer lead
endotoxin neutralization
Research Summary
Preclinical studies report membrane-active killing of bacteria and some activity against cancer cell lines. Multiple analogs have been developed to reduce toxicity while preserving potency.
Related Peptides
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Piscidin-3 is a closely related 22-residue marine fish peptide from the piscidin family. It shows potent membrane-active antimicrobial effects and has been studied for host-defense and anti-biofilm applications.
Marine-DerivedClavanin A
Clavanin A (tunicate-derived antimicrobial peptide)
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Marine-DerivedEpinecidin-1
Epinecidin-1 (orange-spotted grouper antimicrobial peptide)
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Marine-Derivedomega-conotoxin MVIIA
Ziconotide
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Marine-Derived