omega-conotoxin MVIIA
Ziconotide
25 Amino Acids · MW: 2639 Da
Amino Acids
25
Molecular Weight
2639 Da
Half-life
4.5 h (CSF)
Research Score
5.0
Studies
78
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is omega-conotoxin MVIIA?
A 25-amino-acid disulfide-rich peptide isolated from the marine cone snail Conus magus. It selectively blocks N-type calcium channels and is one of the best-known marine peptide therapeutics for severe pain.
Key Benefits & Mechanisms
analgesic
ion-channel blocker
neuroactive
Research Summary
Foundational marine peptide drug; approved as ziconotide for intrathecal treatment of severe chronic pain when other therapies fail.
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