Parathyroid hormone (1-84)
Human parathyroid hormone full-length peptide
84 Amino Acids · MW: about 9.48 kDa
Amino Acids
84
Molecular Weight
about 9.48 kDa
Half-life
about 1 hour
Research Score
3.9
Studies
74
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Parathyroid hormone (1-84)?
Parathyroid hormone (1-84) is the full-length native human PTH molecule. Intermittent exposure can drive bone remodeling toward bone formation, and it remains clinically relevant in calcium-bone disorders.
Key Benefits & Mechanisms
supports bone remodeling
can increase BMD
physiologic PTH replacement
Research Summary
This peptide has been used clinically for hypoparathyroidism and has been explored for skeletal effects in bone metabolism. Its role in osteoporosis is less established than teriparatide, but it is still a real bone-active peptide with human data.
Related Peptides
Abaloparatide
Parathyroid hormone-related protein (PTHrP) analog
Abaloparatide is a synthetic 34-amino-acid analog derived from PTHrP signaling biology. It preferentially activates the PTH1 receptor in a way that supports bone formation with less calcium burden than some older agents.
Bone & JointParathyroid hormone-related protein (1-36)
N-terminal PTHrP fragment
Parathyroid hormone-related protein (1-36) is an N-terminal fragment that activates the same receptor family as PTH. It has been studied as a potential bone-anabolic peptide in preclinical osteoporosis and osteoblast models.
Bone & JointCK2.3
BMP receptor II-derived CK2.3 peptide
CK2.3 is a synthetic peptide derived from the BMP receptor signaling region and studied as an anabolic bone and joint-tissue modulator. Preclinical work suggests it can promote bone formation and may help preserve cartilage in osteoarthritis models.
Bone & Joint