Obestatin
Obestatin (preproghrelin-derived peptide)
23 Amino Acids · MW: N/A
Amino Acids
23
Molecular Weight
N/A
Half-life
N/A
Research Score
3.1
Studies
180
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Obestatin?
Obestatin is a 23-amino-acid peptide encoded by the same preproghrelin gene that gives rise to ghrelin. Its effects on the GH axis are more complex and less consistent than ghrelin, but it remains a real literature-based endocrine modulator.
Key Benefits & Mechanisms
GH-axis modulation
endocrine research tool
may influence appetite signaling
may influence glucose homeostasis
Research Summary
Obestatin has been examined as a counter-regulatory peptide within the ghrelin axis, although its receptor biology and physiological role remain debated. Published work reports mixed findings on GH secretion, making it a useful but controversial GH-pathway probe.
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