Modified GRF(1-29)
[D-Ala2, Nle27]-human growth hormone-releasing hormone (1-29) amide
29 Amino Acids · MW: N/A
Amino Acids
29
Molecular Weight
N/A
Half-life
10-30 minutes
Research Score
4.8
Studies
150
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Modified GRF(1-29)?
A synthetic GHRH analog built from the biologically active 1-29 core with substitutions that improve potency and resistance to degradation. It is one of the best-known research GHRH analogs in the literature and is commonly discussed in the context of GH secretion studies.
Key Benefits & Mechanisms
enhanced GH release
greater peptide stability
IGF-1 support research
longer receptor engagement
Research Summary
Modified GRF(1-29) has been studied as a practical GHRH analog for boosting GH release while improving peptide stability versus the native fragment. It is a standard reference compound in experimental work on growth hormone pulsatility and analog design.
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