L-692,585
L-692,585 (early nonpeptide growth hormone secretagogue receptor agonist)
N/A Amino Acids · MW: N/A
Amino Acids
N/A
Molecular Weight
N/A
Half-life
N/A
Research Score
3.7
Studies
70
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is L-692,585?
L-692,585 is an early Merck nonpeptide secretagogue that showed the feasibility of orally active GH-axis stimulators. It is a classic research compound used to validate the growth hormone secretagogue receptor pathway in vivo.
Key Benefits & Mechanisms
stimulates GH release
validates GHSR biology
orally active in research models
supports IGF-1 signaling studies
Research Summary
L-692,585 was among the first compounds to demonstrate that the GH secretagogue effect could be achieved with a small molecule rather than a peptide. Its literature is foundational to the development of later ghrelin mimetics and GH secretagogue drugs.
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