Venom-DerivedPre-clinical

ImI

alpha-Conotoxin ImI

13 Amino Acids · MW: about 1.6 kDa

Amino Acids

13

Molecular Weight

about 1.6 kDa

Half-life

N/A

Research Score

4.2

Studies

85

Storage

Store lyophilized at -20°C, reconstituted at 2-8°C

What is ImI?

A small disulfide-rich cone snail peptide from Conus imperialis that targets nicotinic acetylcholine receptors. It is widely used as a molecular probe for receptor subtype selectivity and ion-channel pharmacology.

Key Benefits & Mechanisms

nAChR selectivity

neuroscience probe

lead scaffold

Research Summary

ImI is one of the classic alpha-conotoxins used to study alpha7 and related nicotinic receptor subtypes. It remains a valuable lead for mapping cholinergic signaling and designing selective ligands.