Psalmotoxin-1
Psalmotoxin-1 (PcTx1)
40 Amino Acids · MW: 4.3 kDa
Amino Acids
40
Molecular Weight
4.3 kDa
Half-life
Unknown
Research Score
4.6
Studies
88
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Psalmotoxin-1?
Psalmotoxin-1 is a tarantula venom peptide that selectively inhibits acid-sensing ion channel 1a. It is widely used to study pain signaling, ischemia, and neurodegenerative mechanisms.
Key Benefits & Mechanisms
pain research
neuroprotection research
ASIC1a selectivity
Research Summary
One of the best-characterized selective ASIC1a blockers. It is used to dissect proton-gated channel biology and to explore analgesic and neuroprotective strategies.
Related Peptides
Eptifibatide
Eptifibatide
Eptifibatide is a cyclic heptapeptide antiplatelet drug derived from the barbourin motif of pygmy rattlesnake venom. It blocks the platelet glycoprotein IIb/IIIa receptor and is used to reduce thrombotic risk in acute coronary settings.
Venom-DerivedCrotamine
Crotamine
Crotamine is a basic 42-residue peptide from South American rattlesnake venom. It is a cell-penetrating toxin studied as a probe for ion channels and as a potential tumor-targeting delivery scaffold.
Venom-DerivedEchistatin
Echistatin
Echistatin is a small RGD-containing disintegrin from saw-scaled viper venom. It binds integrins and inhibits platelet adhesion, making it a classic tool in thrombosis and cell-adhesion research.
Venom-DerivedCharybdotoxin
Charybdotoxin
Charybdotoxin is a scorpion venom peptide that blocks several potassium channels, especially large-conductance calcium-activated potassium channels. It is a foundational electrophysiology tool for mapping channel function and selectivity.
Venom-Derived