HBD-3
Human Beta-Defensin 3
45 Amino Acids · MW: 5158 Da
Amino Acids
45
Molecular Weight
5158 Da
Half-life
Minutes to hours; protease-sensitive
Research Score
4.8
Studies
380
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is HBD-3?
Human beta-defensin 3 is a potent endogenous antimicrobial peptide expressed by skin and mucosal epithelia. It is known for strong membrane-disrupting activity and for modulating innate immune responses.
Key Benefits & Mechanisms
strong antimicrobial activity
skin and mucosal defense
innate immune signaling modulation
wound-healing support
Research Summary
Human beta-defensin 3 has been examined in numerous in vitro and animal studies for antimicrobial and immunomodulatory activity. Research suggests it can help defend barrier tissues while influencing cytokine networks, chemotaxis, and epithelial repair.
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