HBD-2
Human Beta-Defensin 2
41 Amino Acids · MW: 4316 Da
Amino Acids
41
Molecular Weight
4316 Da
Half-life
Minutes to hours; protease-sensitive
Research Score
4.7
Studies
420
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is HBD-2?
Human beta-defensin 2 is an endogenous cationic antimicrobial peptide produced by epithelial tissues as part of the innate immune response. It has broad activity against bacteria and can also influence chemotaxis and inflammatory signaling.
Key Benefits & Mechanisms
broad-spectrum antimicrobial activity
epithelial barrier defense
innate immune modulation
anti-biofilm potential
Research Summary
Human beta-defensin 2 has been studied extensively for direct microbicidal effects and for its role in shaping mucosal immunity. Preclinical work shows activity against Gram-negative and Gram-positive organisms, with additional effects on leukocyte recruitment and wound defense.
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