HNG
Humanin G (S14G humanin)
24 Amino Acids · MW: 2641.2
Amino Acids
24
Molecular Weight
2641.2
Half-life
minutes to hours
Research Score
4.4
Studies
82
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is HNG?
HNG is a single-amino-acid humanin analog created by replacing serine with glycine at position 14. The substitution is reported to increase the peptide's cytoprotective potency and mitochondrial stress-buffering activity.
Key Benefits & Mechanisms
enhanced cytoprotection
mitochondrial resilience
anti-apoptotic signaling
Research Summary
In cell and animal models HNG has shown stronger protection against oxidative stress, ischemia, and apoptosis than native humanin. It remains investigational and is not standardized for clinical dosing.
Related Peptides
SHLP2
Small Humanin-Like Peptide 2
SHLP2 is a mitochondrial-derived peptide encoded in the mitochondrial 16S rRNA region. It has been investigated for roles in metabolic regulation, cell-survival signaling, and mitochondrial function, but published data remain limited.
MitochondrialSHLP6
Small Humanin-Like Peptide 6
Another member of the small humanin-like peptide family derived from mitochondrial genetic regions. It is studied in early-stage mitochondrial signaling and metabolic regulation research.
Mitochondrial