gp100 209-217
IMDQVPFSV melanoma antigen peptide
9 Amino Acids · MW: 1034.2
Amino Acids
9
Molecular Weight
1034.2
Half-life
<1 h
Research Score
4.4
Studies
84
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is gp100 209-217?
An HLA-A2-restricted melanoma epitope derived from gp100. It is used in therapeutic vaccine research to prime cytotoxic T cells against melanoma cells.
Key Benefits & Mechanisms
CTL priming
tumor-antigen specificity
vaccine compatibility
Research Summary
gp100 peptide vaccines have been evaluated in melanoma to increase antigen-specific CD8+ T-cell responses. The peptide is a classic research epitope in cancer immunotherapy and is often combined with adjuvants or checkpoint blockade.
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