LongevityPre-clinical

GHK

Glycyl-Histidyl-Lysine Tripeptide

3 Amino Acids · MW: 340.38 Da

Amino Acids

3

Molecular Weight

340.38 Da

Half-life

~2 hours

Research Score

4.5

Studies

178

Storage

N/A

What is GHK?

GHK is the copper-free form of the well-known GHK-Cu tripeptide. It naturally occurs in human plasma and declines significantly with age. Even without copper, GHK influences gene expression of over 4,000 human genes, many involved in tissue remodeling, DNA repair, and antioxidant defenses.

Key Benefits & Mechanisms

Modulates 4,000+ gene expressions

DNA repair and protection

Antioxidant system activation

Tissue remodeling

Anti-cancer gene activation

Suppresses metastasis-related genes

Stem cell attraction to injury sites

Research Summary

GHK has been studied for over 40 years. Genomic studies reveal it upregulates genes associated with tissue repair and suppresses genes associated with disease. Research by Dr. Loren Pickart demonstrates broad gene modulatory effects relevant to aging and disease prevention.