FS315
Follistatin-315 (FS315)
315 Amino Acids · MW: ~40 kDa
Amino Acids
315
Molecular Weight
~40 kDa
Half-life
N/A; depends on construct/delivery
Research Score
4.0
Studies
95
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is FS315?
The circulating major isoform of follistatin that binds activins and can modulate myostatin signaling. It is widely used in research because it is the more common endogenous secreted form in human plasma.
Key Benefits & Mechanisms
activin neutralization
muscle growth signaling
anti-catabolic support
tissue repair modulation
Research Summary
Follistatin-315 is a key reference isoform in studies of muscle anabolism and reproductive/endocrine biology. In muscle research, it is relevant because it suppresses activin and can indirectly blunt myostatin pathway output.
Related Peptides
ACE-031
ACE-031 (soluble activin receptor type IIB-Fc)
A recombinant decoy receptor fusion protein that traps myostatin and related ligands such as activins. It was developed to promote skeletal muscle growth and counteract wasting.
Muscle & PerformanceBYM338
Bimagrumab (BYM338)
A human monoclonal antibody against activin type II receptors that blocks myostatin/activin signaling at the receptor level. It has been studied for sarcopenia, obesity with muscle preservation, and several wasting conditions.
Muscle & PerformanceREGN1033
Trevogrumab (REGN1033)
A human monoclonal antibody that neutralizes myostatin, the key negative regulator of skeletal muscle growth. It has been evaluated for muscle loss states and as a body-composition modulator in combination regimens.
Muscle & PerformanceEpoetin Alfa
Recombinant human erythropoietin alfa
Recombinant human erythropoietin alfa is a glycoprotein hormone that stimulates red blood cell production. In endurance contexts, its main effect is improving oxygen delivery and potentially raising VO2 max, but the safety margin is narrow.
Muscle & Performance