ACE-031
ACE-031 (soluble activin receptor type IIB-Fc)
N/A Amino Acids · MW: ~95 kDa
Amino Acids
N/A
Molecular Weight
~95 kDa
Half-life
Days to weeks
Research Score
4.4
Studies
75
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is ACE-031?
A recombinant decoy receptor fusion protein that traps myostatin and related ligands such as activins. It was developed to promote skeletal muscle growth and counteract wasting.
Key Benefits & Mechanisms
myostatin/activin neutralization
lean mass gain
muscle function support
anti-catabolic effect
Research Summary
ACE-031 produced increases in lean mass in early studies, but development was curtailed after safety concerns and variable efficacy. Its literature remains important because it validated activin receptor blockade as a muscle-building strategy.
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