ET-1
Endothelin-1
21 Amino Acids · MW: 2492.95
Amino Acids
21
Molecular Weight
2492.95
Half-life
4-7 min
Research Score
4.6
Studies
75
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is ET-1?
A 21-amino-acid peptide with two disulfide bonds that is among the most potent endogenous vasoconstrictors. It signals through ETA and ETB receptors to control vascular tone and smooth muscle growth.
Key Benefits & Mechanisms
vasoactive
mitogenic
cardiovascular
Research Summary
A major peptide mediator in pulmonary and systemic vascular disease. Endothelin signaling is a validated target in pulmonary arterial hypertension research and therapy.
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