BK
Bradykinin
RPPGFSPFR Amino Acids · MW: 1060.2
Amino Acids
RPPGFSPFR
Molecular Weight
1060.2
Half-life
<1 min
Research Score
4.2
Studies
85
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is BK?
A nonapeptide generated from kininogen during inflammation and tissue injury. It activates B1/B2 receptors to produce vasodilation, pain, and vascular permeability.
Key Benefits & Mechanisms
vasodilation
pain signaling
vascular permeability
Research Summary
A canonical signaling peptide in the kallikrein-kinin system, heavily studied for inflammation, nociception, and vascular physiology.
Related Peptides
IGF-1
Insulin-like growth factor 1
A 70-amino-acid peptide that signals through IGF1R to activate PI3K/AKT and MAPK pathways. It mediates anabolic growth, cell survival, and tissue repair in endocrine and local paracrine signaling.
Signal PeptidesAVP
Arginine vasopressin
A nonapeptide hormone that acts at V1 and V2 receptors to regulate vascular tone and renal water reabsorption. It is a core mediator of osmotic homeostasis and blood pressure control.
Signal PeptidesANG II
Angiotensin II
An 8-amino-acid peptide hormone that binds angiotensin receptors to drive vasoconstriction, aldosterone release, and thirst. It is a major signaling effector of the renin-angiotensin system.
Signal PeptidesET-1
Endothelin-1
A 21-amino-acid peptide with two disulfide bonds that is among the most potent endogenous vasoconstrictors. It signals through ETA and ETB receptors to control vascular tone and smooth muscle growth.
Signal Peptides