Edratide
Human Complementarity-Determining Region 1 Peptide (hCDR1)
19 Amino Acids · MW: ≈2,100 Da
Amino Acids
19
Molecular Weight
≈2,100 Da
Half-life
Minutes to hours
Research Score
3.9
Studies
25
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Edratide?
A synthetic peptide derived from the complementarity-determining region 1 of a human anti-DNA antibody. It was developed as an autoimmune-modulating peptide for systemic lupus erythematosus research.
Key Benefits & Mechanisms
autoimmune modulation
immune tolerance support
anti-dsDNA response reduction
anti-inflammatory cytokine shift
Research Summary
hCDR1/edratide was studied in systemic lupus erythematosus with the goal of restoring immune tolerance rather than broadly suppressing immunity. Research focused on reducing autoreactivity and shifting cytokine profiles toward a less inflammatory state.
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