Cenegermin
Recombinant human nerve growth factor
118 Amino Acids · MW: ≈13.6 kDa
Amino Acids
118
Molecular Weight
≈13.6 kDa
Half-life
minutes to hours locally
Research Score
4.9
Studies
92
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Cenegermin?
A recombinant human NGF eye drop used to promote corneal nerve regeneration in neurotrophic keratitis. It is the only ophthalmic peptide in this list with regulatory approval.
Key Benefits & Mechanisms
corneal nerve regeneration
epithelial healing
pain reduction
Research Summary
Approved as Oxervate for neurotrophic keratitis. Multiple trials showed improved corneal healing versus vehicle in patients with persistent epithelial defects.
Related Peptides
NGF
Beta-Nerve Growth Factor (human NGF beta)
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Cognitive EnhancementAngiotensin-(1-7)
Angiotensin 1-7
Angiotensin-(1-7) is a seven-amino-acid peptide from the renin-angiotensin system with reported retinal and corneal biology. Ocular studies have explored it for anti-fibrotic, anti-inflammatory, and vascular effects.
OphthalmicCyclosporine A
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Renin-angiotensin octapeptide
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Ophthalmic