Bombesin
Bombesin (GRPR-targeting peptide scaffold)
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 Amino Acids · MW: 1619.90 Da
Amino Acids
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
Molecular Weight
1619.90 Da
Half-life
about 2-5 minutes
Research Score
3.8
Studies
74
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Bombesin?
Bombesin is a classic gastrin-releasing peptide receptor scaffold used in diagnostic tracer development. Radiolabeled bombesin analogs have been investigated for prostate, breast, and pancreatic cancer imaging because GRPR is frequently overexpressed in these tumors.
Key Benefits & Mechanisms
GRPR targeting
tumor imaging scaffold
strong literature support
Research Summary
Bombesin analogs remain a major research platform for GRPR imaging, with many 68Ga-, 64Cu-, 18F-, and 99mTc-labeled derivatives reported. The native peptide and its analogs are widely cited in the molecular imaging literature for receptor-positive tumors.
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