Amyloid beta 1-42
Amyloid beta peptide 1-42 (Aβ1-42)
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA Amino Acids · MW: 4.51 kDa
Amino Acids
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight
4.51 kDa
Half-life
minutes to hours
Research Score
4.9
Studies
96
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is Amyloid beta 1-42?
A 42-aa peptide derived from amyloid precursor protein and a core biomarker for Alzheimer-type amyloid pathology. In CSF and plasma testing, it is often interpreted together with Aβ1-40 using the Aβ42/40 ratio to improve diagnostic performance.
Key Benefits & Mechanisms
alzheimer's biomarker
CSF ratio testing
amyloid pathology assessment
Research Summary
Aβ42 is a key analyte in modern Alzheimer's biomarker frameworks; immunoassays and mass-spectrometry methods use it to support amyloid status assessment.
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Diagnostic Peptides