BMS-202
Small-molecule PD-L1 dimerization inhibitor BMS-202
N/A Amino Acids · MW: N/A
Amino Acids
N/A
Molecular Weight
N/A
Half-life
Unknown
Research Score
4.1
Studies
60
Storage
Store lyophilized at -20°C, reconstituted at 2-8°C
What is BMS-202?
BMS-202 is a benzimidazole-based research compound that inhibits the PD-1/PD-L1 interaction by stabilizing PD-L1 homodimers. It is widely used as a tool molecule in checkpoint biology and immuno-oncology screening.
Key Benefits & Mechanisms
PD-L1 inhibition
checkpoint pathway mapping
T-cell restoration research
combination screening
Research Summary
BMS-202 helped validate the concept that small molecules can directly block PD-L1-mediated immune evasion. It remains a preclinical reference compound rather than a clinical drug.
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