Tianeptine sodium vs NGF
Head-to-head comparison of Tianeptine sodium (Tianeptine sodium) and NGF (Beta-Nerve Growth Factor (human NGF beta)) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Tianeptine sodium | NGF |
|---|---|---|
| Category | Cognitive Enhancement | Cognitive Enhancement |
| Full Name | Tianeptine sodium | Beta-Nerve Growth Factor (human NGF beta) |
| Molecular Weight | 458.94 Da | 13,600 Da |
| Half-Life | About 2.5 hours | hours |
| Amino Acids | N/A | 118 aa |
| Typical Dose | 12.5 mg 3 times daily | research-only microgram range |
| Route | Oral | Intranasal |
| Purity | ≥98% | ≥98% |
| Studies Count | 280 | 3500 |
| Research Status | Clinical | Pre-clinical |
Tianeptine sodium Benefits
- ✓mood improvement
- ✓anxiety reduction
- ✓cognitive clarity
- ✓stress adaptation
NGF Benefits
- ✓neurite outgrowth
- ✓cholinergic support
- ✓nerve repair
- ✓neuroprotection
Tianeptine sodium Dosing
12.5 mg oral 3x/day|25 mg/day oral|clinical antidepressant dosing
NGF Dosing
0.01-1 µg/kg in experimental delivery studies|local CNS or intranasal research delivery|single or repeated low-dose protocols
Tianeptine sodium Side Effects
- ⚠nausea
- ⚠dizziness
- ⚠dependence risk
NGF Side Effects
- ⚠pain at injection site
- ⚠hyperalgesia
- ⚠autonomic effects
Research Overview
Tianeptine sodium
Clinical studies support tianeptine as an antidepressant with a distinctive glutamatergic and neuroplasticity-related profile. Some evidence suggests cognitive benefits in mood-impaired populations, likely secondary to improved stress handling and affect.
NGF
NGF is one of the most established growth factors in neurobiology and has been investigated for both central and peripheral neuronal repair. Its strongest cognitive relevance comes from supporting basal forebrain cholinergic neurons and downstream memory circuitry.
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