Tianeptine sodium vs Noopept
Head-to-head comparison of Tianeptine sodium (Tianeptine sodium) and Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Tianeptine sodium | Noopept |
|---|---|---|
| Category | Cognitive Enhancement | Cognitive Enhancement |
| Full Name | Tianeptine sodium | N-phenylacetyl-L-prolylglycine ethyl ester |
| Molecular Weight | 458.94 Da | 318.37 Da |
| Half-Life | About 2.5 hours | 20-30 minutes |
| Amino Acids | N/A | N/A |
| Typical Dose | 12.5 mg 3 times daily | 10-30 mg/day |
| Route | Oral | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 280 | 60 |
| Research Status | Clinical | Clinical |
Tianeptine sodium Benefits
- ✓mood improvement
- ✓anxiety reduction
- ✓cognitive clarity
- ✓stress adaptation
Noopept Benefits
- ✓memory recall
- ✓learning efficiency
- ✓attention support
- ✓neurotrophic signaling
Tianeptine sodium Dosing
12.5 mg oral 3x/day|25 mg/day oral|clinical antidepressant dosing
Noopept Dosing
oral research use|10-30 mg per day in human studies|divided or single daily dosing
Tianeptine sodium Side Effects
- ⚠nausea
- ⚠dizziness
- ⚠dependence risk
Noopept Side Effects
- ⚠headache
- ⚠irritability
- ⚠sleep disturbance
Research Overview
Tianeptine sodium
Clinical studies support tianeptine as an antidepressant with a distinctive glutamatergic and neuroplasticity-related profile. Some evidence suggests cognitive benefits in mood-impaired populations, likely secondary to improved stress handling and affect.
Noopept
Noopept has been reported to increase NGF/BDNF-related signaling and improve performance in tasks involving learning and recall. Evidence includes preclinical studies and small human studies, but the overall literature is still modest compared with mainstream cognitive drugs.
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