Secretin vs Hexarelin
Head-to-head comparison of Secretin (Human Secretin) and Hexarelin (Growth Hormone Releasing Hexapeptide) — benefits, dosing, side effects, research data, and where to buy.
| Property | Secretin | Hexarelin |
|---|---|---|
| Category | Gastrointestinal | Performance |
| Full Name | Human Secretin | Growth Hormone Releasing Hexapeptide |
| Molecular Weight | 3055.4 Da | 887.04 Da |
| Half-Life | 5-7 minutes | ~70 minutes |
| Amino Acids | 27 | 6 |
| Typical Dose | 0.2 mcg/kg IV | 100-200 mcg |
| Route | Intravenous | SC / IV |
| Purity | ≥98% | — |
| Studies Count | 800 | 198 |
| Research Status | Clinical | Clinical Trials |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
Hexarelin Benefits
- ✓Strongest GH pulse among GHRPs
- ✓Cardioprotective effects
- ✓Muscle mass and strength gains
- ✓Fat loss through improved body composition
- ✓Enhanced recovery from training
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
Hexarelin Dosing
Standard: 100-200 mcg SC 2-3 times daily|Pre-workout: 100 mcg 30 min before training|Pre-bed: 100 mcg for overnight GH pulse|Cycle: 8-12 weeks then 4 week break (desensitization)
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
Hexarelin Side Effects
- ⚠Common: Increased appetite, water retention, tingling
- ⚠Moderate: Cortisol and prolactin elevation (dose-dependent)
- ⚠Notable: Desensitization occurs after 4-16 weeks of continuous use
- ⚠Rare: Numbness in extremities
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
Hexarelin
Hexarelin has extensive pre-clinical and clinical evidence. Multiple human studies confirm potent GH release. Unique cardioprotective properties are well-documented. Note that receptor desensitization limits long-term continuous use.
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