Secretin vs GHRP-6
Head-to-head comparison of Secretin (Human Secretin) and GHRP-6 (Growth Hormone Releasing Peptide-6) — benefits, dosing, side effects, research data, and where to buy.
| Property | Secretin | GHRP-6 |
|---|---|---|
| Category | Gastrointestinal | Performance |
| Full Name | Human Secretin | Growth Hormone Releasing Peptide-6 |
| Molecular Weight | 3055.4 Da | 873.01 Da |
| Half-Life | 5-7 minutes | ~15-60 minutes |
| Amino Acids | 27 | 6 |
| Typical Dose | 0.2 mcg/kg IV | 100-300 mcg |
| Route | Intravenous | SC / IV |
| Purity | ≥98% | — |
| Studies Count | 800 | 186 |
| Research Status | Clinical | Clinical Trials |
Secretin Benefits
- ✓stimulates-pancreatic-secretion
- ✓supports-bicarbonate-release
- ✓aids-duodenal-pH-control
- ✓helps-digestive-coordination
GHRP-6 Benefits
- ✓Potent GH release stimulation
- ✓Muscle growth and strength
- ✓Appetite stimulation (ghrelin pathway)
- ✓Improved body composition
- ✓Enhanced recovery from training
Secretin Dosing
0.2 mcg/kg IV diagnostic dose|research infusion protocols|short bolus administration
GHRP-6 Dosing
Standard: 100-300 mcg SC 2-3 times daily|Pre-workout: 100 mcg 30 min before training|Pre-bed: 100-200 mcg for overnight GH pulse
Secretin Side Effects
- ⚠flushing
- ⚠nausea
- ⚠abdominal-cramping
GHRP-6 Side Effects
- ⚠Common: Increased appetite (significant), water retention, tingling
- ⚠Moderate: Cortisol elevation (dose-dependent), lethargy
- ⚠Rare: Elevated prolactin at high doses
Research Overview
Secretin
Secretin is a classic GI hormone with extensive physiology literature and established diagnostic use. It remains important for studying pancreatic secretory function, biliary responses, and duodenal feedback.
GHRP-6
GHRP-6 has solid pre-clinical and clinical evidence for GH stimulation. Well-characterized pharmacology. More appetite stimulation than Ipamorelin due to ghrelin receptor activation.
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