Resveratrol vs Pterostilbene
Head-to-head comparison of Resveratrol (trans-3,5,4'-Trihydroxystilbene) and Pterostilbene (trans-3,5-Dimethoxy-4'-hydroxystilbene) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Resveratrol | Pterostilbene |
|---|---|---|
| Category | Anti-Aging | Anti-Aging |
| Full Name | trans-3,5,4'-Trihydroxystilbene | trans-3,5-Dimethoxy-4'-hydroxystilbene |
| Molecular Weight | 228.24 Da | 256.31 Da |
| Half-Life | 1-3 hours | 2-4 hours |
| Amino Acids | N/A | N/A |
| Typical Dose | 100-500 mg/day | 50-150 mg/day |
| Route | Oral | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 900 | 95 |
| Research Status | Clinical | Clinical |
Resveratrol Benefits
- ✓activates sirtuin/AMPK pathways
- ✓supports mitochondrial biogenesis
- ✓antioxidant effects
- ✓may improve metabolic health
Pterostilbene Benefits
- ✓better bioavailability than resveratrol
- ✓antioxidant/anti-inflammatory
- ✓supports metabolic health
- ✓may support cognitive aging
Resveratrol Dosing
100-500 mg/day orally|split doses with meals|long-term trial periods
Pterostilbene Dosing
50-150 mg/day orally|once daily with food|multi-week study periods
Resveratrol Side Effects
- ⚠GI upset
- ⚠loose stools
- ⚠drug interaction risk
Pterostilbene Side Effects
- ⚠GI upset
- ⚠increased LDL in some studies
- ⚠headache
Research Overview
Resveratrol
Resveratrol has extensive preclinical literature and a substantial human trial history in metabolic and aging-related endpoints. Results are mixed, but it remains one of the most studied longevity-associated compounds.
Pterostilbene
Pterostilbene has supportive preclinical data and smaller human studies across metabolic and oxidative stress endpoints. Its anti-aging potential is plausible, but it is less established than resveratrol or NR.
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