Pterostilbene vs Urolithin A
Head-to-head comparison of Pterostilbene (trans-3,5-Dimethoxy-4'-hydroxystilbene) and Urolithin A (Urolithin A) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Pterostilbene | Urolithin A |
|---|---|---|
| Category | Anti-Aging | Anti-Aging |
| Full Name | trans-3,5-Dimethoxy-4'-hydroxystilbene | Urolithin A |
| Molecular Weight | 256.31 Da | 228.20 Da |
| Half-Life | 2-4 hours | N/A |
| Amino Acids | N/A | N/A |
| Typical Dose | 50-150 mg/day | 250-1000 mg/day |
| Route | Oral | Oral |
| Purity | ≥98% | ≥98% |
| Studies Count | 95 | 120 |
| Research Status | Clinical | Clinical |
Pterostilbene Benefits
- ✓better bioavailability than resveratrol
- ✓antioxidant/anti-inflammatory
- ✓supports metabolic health
- ✓may support cognitive aging
Urolithin A Benefits
- ✓mitophagy activation
- ✓muscle endurance support
- ✓mitochondrial health
- ✓cellular cleanup
Pterostilbene Dosing
50-150 mg/day orally|once daily with food|multi-week study periods
Urolithin A Dosing
250-1000 mg/day oral|daily capsule dosing in studies|single daily dose protocols
Pterostilbene Side Effects
- ⚠GI upset
- ⚠increased LDL in some studies
- ⚠headache
Urolithin A Side Effects
- ⚠nausea
- ⚠GI discomfort
- ⚠headache
- ⚠bloating
Research Overview
Pterostilbene
Pterostilbene has supportive preclinical data and smaller human studies across metabolic and oxidative stress endpoints. Its anti-aging potential is plausible, but it is less established than resveratrol or NR.
Urolithin A
Urolithin A has both animal and human data showing effects on mitochondrial biomarkers and physical performance-related endpoints. It is one of the more promising mitochondrial-targeted longevity compounds in current literature.
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