rhPDGF-BB vs BMP-7
Head-to-head comparison of rhPDGF-BB (Recombinant Human Platelet-Derived Growth Factor-BB) and BMP-7 (Recombinant Human Bone Morphogenetic Protein-7) — benefits, dosing, side effects, research data, and where to buy.
| Property | rhPDGF-BB | BMP-7 |
|---|---|---|
| Category | Recovery & Healing | Recovery & Healing |
| Full Name | Recombinant Human Platelet-Derived Growth Factor-BB | Recombinant Human Bone Morphogenetic Protein-7 |
| Molecular Weight | 24.8 kDa | 35000 Da |
| Half-Life | minutes | short, localized exposure |
| Amino Acids | 109 per chain (homodimer) | 139 |
| Typical Dose | 100 µg/g gel once daily | procedure-dependent local implant |
| Route | Topical | Local/Implant |
| Purity | ≥98% | ≥98% |
| Studies Count | 400 | 700 |
| Research Status | Clinical | Clinical |
rhPDGF-BB Benefits
- ✓cell migration
- ✓fibroblast proliferation
- ✓collagen deposition
- ✓diabetic ulcer healing
BMP-7 Benefits
- ✓supports bone formation
- ✓may aid nonunion repair
- ✓promotes connective tissue regeneration
- ✓helps scaffold integration
rhPDGF-BB Dosing
Topical once daily|apply to clean wound bed|continue until complete granulation/closure
BMP-7 Dosing
local implantation|single procedural exposure|research or device-specific delivery
rhPDGF-BB Side Effects
- ⚠local erythema
- ⚠pain
- ⚠edema
- ⚠theoretical tumor-promoting risk
BMP-7 Side Effects
- ⚠local swelling
- ⚠inflammation
- ⚠ectopic mineralization
Research Overview
rhPDGF-BB
rhPDGF-BB has one of the strongest clinical wound-healing datasets among growth factors and is best known for chronic diabetic foot ulcers. Its efficacy is tied to chemotaxis and mitogenesis in fibroblasts, smooth muscle cells, and macrophage-lineage cells.
BMP-7
rhBMP-7 has a long history in preclinical and clinical literature for bone repair, particularly in challenging healing environments. Its cartilage-related research is less mature than BMP-2 but still relevant to musculoskeletal regeneration.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.