Omentin-1 vs Kisspeptin-52

Head-to-head comparison of Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) and Kisspeptin-52 (Kisspeptin-52 (KISS1-derived peptide fragment)) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyOmentin-1Kisspeptin-52
CategoryDiabetes & MetabolicSexual Health
Full NameOmentin-1 (Intelectin-1, ITLN1)Kisspeptin-52 (KISS1-derived peptide fragment)
Molecular Weight~35 kDa≈5,800 Da
Half-LifehoursMinutes to ~1 hour
Amino Acids31352
Typical DoseNo approved human dose; research use only0.1-3.0 nmol/kg
RouteIV|SCIntravenous/Subcutaneous
Purity≥98%≥98%
Studies Count82120
Research StatusPre-clinicalClinical research

Omentin-1 Benefits

  • insulin sensitivity
  • glucose uptake
  • lipid handling

Kisspeptin-52 Benefits

  • stimulates GnRH signaling
  • supports LH/FSH release
  • aids ovulation research
  • maps reproductive-axis function

Omentin-1 Dosing

not established|not established

Kisspeptin-52 Dosing

0.1-3.0 nmol/kg IV bolus|0.1-1.0 nmol/kg SC|protocol-dependent infusion

Omentin-1 Side Effects

  • unknown
  • immunogenicity risk

Kisspeptin-52 Side Effects

  • flushing
  • nausea
  • headache

Research Overview

Omentin-1

Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.

Kisspeptin-52

Human and animal studies show kisspeptin-52 can acutely increase gonadotropin secretion and activate the hypothalamic-pituitary-gonadal axis. It has been explored in fertility research and assisted-reproduction settings as a way to trigger endogenous reproductive hormone release.

Ready to buy?

Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.

Common Stacking Partners

Omentin-1 stacks with:

Intelectin-1ITLN1

Kisspeptin-52 stacks with:

FSHhCG
AMPKadipokineinsulin-sensitizingbiomarkerkisspeptingonadotropinfertility