Omentin-1 vs Bremelanotide
Head-to-head comparison of Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) and Bremelanotide (Bremelanotide (PT-141), cyclic melanocortin receptor agonist) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Omentin-1 | Bremelanotide |
|---|---|---|
| Category | Diabetes & Metabolic | Sexual Health |
| Full Name | Omentin-1 (Intelectin-1, ITLN1) | Bremelanotide (PT-141), cyclic melanocortin receptor agonist |
| Molecular Weight | ~35 kDa | 1025.2 Da |
| Half-Life | hours | about 2.7 h |
| Amino Acids | 313 | 7 |
| Typical Dose | No approved human dose; research use only | 1.75 mg |
| Route | IV|SC | Subcutaneous |
| Purity | ≥98% | ≥98% |
| Studies Count | 82 | 200 |
| Research Status | Pre-clinical | Clinical |
Omentin-1 Benefits
- ✓insulin sensitivity
- ✓glucose uptake
- ✓lipid handling
Bremelanotide Benefits
- ✓increases sexual desire
- ✓supports arousal
- ✓may improve erectile response
- ✓on-demand use
Omentin-1 Dosing
not established|not established
Bremelanotide Dosing
1.75 mg subcutaneous PRN|administer about 45 minutes before activity|max 1 dose per 24 hours
Omentin-1 Side Effects
- ⚠unknown
- ⚠immunogenicity risk
Bremelanotide Side Effects
- ⚠nausea
- ⚠flushing
- ⚠headache
- ⚠transient blood pressure increase
Research Overview
Omentin-1
Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.
Bremelanotide
Human studies and approval data support meaningful effects on sexual desire in women, with a central mechanism involving melanocortin signaling. It is one of the most clinically relevant peptides in this category and is commonly used as the reference compound for PT-141-type research.
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